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Results for " HY-16436 " in MedChemExpress (MCE) Product Catalog:

Inhibitors & Agonists

Cat. No. Product Name Target Research Area
  • HY-16436
    Rolapitant hydrochloride hydrate Neurokinin Receptor Neurological Disease; Cancer
    Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model[1][2].

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